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15 Best Things to Do on the Mississippi River

The Sky and Trees Reflection on Mississippi River
Published on: March 5, 2022
Last updated: September 24, 2024

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Jenifer Sako

Written by Jenifer Sako

Jen is a Pittsburgh-based writer with a background in hospitality and tourism. Her specialties include sales and marketing technology and travel content. When she isn't on assignment, Jen catches up on her many newsletter subscriptions, watches nocode tutorials, and spends time with her family.

From the chilly waters of Lake Itasca in Minnesota, a nondescript stream of water begins a 2,300-mile descent, gathering volume as it flows, cutting southward through 10 states, until it reaches the warm Gulf of Mexico near New Orleans.

This is the mighty Mississippi River. It’s one of the largest rivers in the world and the longest in North America. It’s also a natural playground full of history, culture, and recreational opportunities.

There is so much to do and see along its couple thousand miles. Visitors often spend days exploring it on river cruises. But we’re going to break it down so you can plan to have the most fun doing the things that interest you.

From our travels and visitor reviews, we researched all the best things to do by region for families, couples, and groups. We also found some excellent hotel options for your stay.

Then, we put them together in a guide you’ll find helpful as you plan your next vacation to one of the many fun and fascinating cities or towns on the Mississippi River.

As always, weather, illness, and other unpredictable events can ruin a trip faster than you can say, “pass the tissues.” That’s why we always recommend TravelInsurance.com as one of the most responsive travel insurance companies.

Read on to learn about the best ways to enjoy the Mississippi River. Here are the best things to do on the Mississippi River.

Best Museums for Learning the Mississippi River’s History and Culture

The Mississippi River’s history is long and storied. It’s also inspired many songs, books, and folk art. Here are the best places if you want to learn more.

1. National Mississippi River Museum

National Mississippi River Museum Front with American Flag
“National Mississippi River Museum & Aquarium” by puroticorico 

The National Mississippi River Museum, located in Port of Dubuque, Iowa, is part of the Smithsonian Institution with aquariums and other interactive exhibits that tell the natural history story of the great river.

The museum, made of two buildings, and an outdoor plaza, plus the grounds, occupy 14-acres on the banks of the Iowa portion of the river.

It houses over 100 animal species and many historic artifacts. You’ll also get the chance to learn about the famous steam-powered dredge, William M. Black, operated by the U.S. Army Corps of Engineers, kept the navigation channels of the major western rivers clear.

Now moored permanently in the adjacent Ice Harbor, this museum ship offers a self-guided tour to show you what life was like on board for the officers and crewmen.

Besides the Black dredge, Iowa visitors also love the museum’s hands-on exhibits, including touch tanks, and knowledgeable guides. Be aware that the observation tower and the upper deck of the dredge are only accessible by stairs.

This is an ideal place to spend the afternoon as a family. The highly-rated TownPlace Suites by Marriott Downtown Dubuque, Iowa, is only 0.6 miles from the museum.

See Related: Best Iowa Family Vacations

2. Delta Blues Museum

Front and Grounds of Delta Blues Museum
Delta Blues Museum by VitaleBaby at English Wikipedia

Clarksdale was founded at “the crossroads” of Highways 61 and 49 and has been at the center of delta blues culture since the 1920s.

Now it’s home to the oldest music museum in the state. You’ll find it in the Yazoo and Mississippi River Valley Railroad Depot.

The Delta Blues Museum celebrates the musicians and the music that define the blues and is a featured stop for people looking for Mississippi attractions on a Great River Road trip.

Muddy Water’s old shack is here and you can also see photographs, music instruments, and other memorabilia of the artists, from the obscure to the world-famous.

Here visitors get an accurate picture of the lives of their favorite artists. Many commented that the museum is better suited for real fans of blues music, rather than the casual listener.

Also, no photography is allowed and the rule appears to be strictly enforced. Couples or small groups of friends who know blues music would enjoy this museum.

The charming Travelers Hotel is close to the Delta Blues Museum and other things to do in Mississippi and comes highly rated.

3. Vicksburg National Military Park

Monument under the Sky Full of Stars

If you’re a history buff and want to know what to see in Mississippi, go to the site of the Battle of Vicksburg, waged during the American Civil War in 1863 from March 29 to July 4.

The 1,800-acre battlefield is in Vicksburg. Besides commemorating the actual 47-day bloody battle, it also tells the history of the greater Vicksburg Campaign that preceded it.

Easily accessible by car, you can spend as much time here. But if you are into Civil War history, you may want to explore it and Vicksburg over a couple of days.

The battle of Vicksburg’s military history has been overshadowed by the battle of Gettysburg, which occurred over the same week.

Both battles turned the tide of the Civil War decidedly toward the Union, handing them landmark victories, and in the case of Vicksburg, control over the Mississippi. Vicksburg is also as awe-inspiring, solemn, and beautiful as Gettysburg.

The monuments are along a winding road and while the plaques contain a massive amount of information, some people may find it hard to visualize the battle setup.

You also don’t get a bird’s eye view of the river or Vicksburg. However, I recommend seeing it as a sobering reminder of what happens when a country becomes dangerously divided.

Although the Vicksburg National Military Park is educational, young kids may not appreciate its military history importance. But couples and groups of friends who are into Civil War facts will love it.

A reasonably priced accommodation with a pool and WiFi, the Super 8 by Wyndham Vicksburg is close and gets good reviews.

4. Mark Twain Boyhood Home & Museum

Statue Exh9bits Inside Mark Twain Boyhood Home & Museum
“Mark Twain Boyhood Home & Museum” by TaylorStudiosInc 

The museum dedicated to the life and career of beloved American writer and humorist, Mark Twain is in his home on the banks of the Mississippi River in Hannibal, Missouri.

The excellent Interpretative Center starts your visit with displays and a viewing of the Ken Burns documentary about Mark Twain.

Then you’ll be on your way to tour the home and other important buildings to his life where you’ll see an exclusive collection of printed stories, novels, and articles.

You’ll also find permanent and rotating exhibits. Many of Twain’s personal belongings, including his iconic white jacket and one of his pipes, are on display.

It’s an amazing place that follows a young boy named Samuel on his path to becoming one of the greatest American novelists.

Fans of his classic works, especially The Adventures of Tom Sawyer and Adventures of Huckleberry Finn, will especially enjoy the museum.

The historic buildings have a couple of rooms to enter, but you’ll have to look through the windows at the other rooms.

Very young children may not enjoy a visit, but couples or families with older kids who appreciate Twain will gain a better understanding of his life and times.

Best Western on the River is a five-minute walk to the museum and comes highly recommended.

5. Lower Mississippi River Museum

Lower Mississippi River Museum Building with Glass Windows
Jesse Brent Lower Mississippi River Museum by Allaninnman is licensed under CC BY-SA 4.0

This museum is one of the best free things to see in Mississippi, and it’s also in Vicksburg. It’s all about family and community life on the river – as CCR and Lady Tina told us, people on the river are happy to give.

They also have an enormous aquarium for a close-up view of river wildlife. The Lower Mississippi River Museum is smallish, so you can go through it in about an hour.

Your younger kids will find one of the more engaging attractions in Mississippi and they will love the aquarium.

The nearby Home2 Suites by Hilton offers suite rooms with microwaves and kitchenettes. The property also has a very nice pool.

Best Mississippi River State Parks for Outdoor Recreation

What better way to enjoy the great river than a visit to some gorgeous state parks. Fresh air, natural beauty, and sunshine await!

6. Trail of Tears State Park

Overview Look of Mississippi River
Trail of Tears State Park, Missouri by gobucks2

Spreading across almost 3,500 acres bordering the Mississippi River in Missouri, the Trail of Tears State Park commemorates the thousands of Cherokee Native Americans who lost their lives on the Cherokee Trail of Tears.

The visitors center tells the account of the deadly forced march of the Cherokee Native Americans in 1838 and 1839 through poignant exhibits.

Outside are scenic overlooks of the Mississippi River and shady places to picnic. There is also hiking, horseback riding, fishing in the river, and birdwatching.

This is an excellent park for families to learn and play along the Mississippi River. The Drury Inn & Suites in nearby Jackson, Missouri, is a highly rated suite option for overnights.

7. Perrot State Park

Trail and road at Perrot State Park
Hank Erdmann / Adobe Stock

Where the Trempealeau and the Mississippi rivers meet in Wisconsin lies the 1,270-acre Perrot State Park. It’s known for gorgeous limestone bluffs and scenic overlooks of the Mississippi River. Visitors will find great hiking trails and access to the Great River State Trail.

Canoes can be rented to use in Trempealeau Bay. This is a great place for families. Reserve a room nearby Fairfield Inn & Suites in Winona for a clean and comfortable stay.

See Related: Best Things to Do in Winona, Minnesota

8. Mississippi River State Park

Flowers, Plants and Bushes at Mississippi River State Park
Mississippi River State Park by Brandonrush is licensed under CC BY-SA 4.0

The whole family will enjoy boating, fishing, and taking a kayak trip on the Lower Mississippi River here in Arkansas.

The Mississippi River State Park would also make a great stop along the Great River Road. It’s within the beautiful Saint Francis National Forest and has some wonderful hiking trails.

There are several pretty good and reasonably priced hotels and motels nearby. But this Comfort Suites in Forrest City rates highly among past guests.

9. Lake Chicot State Park

Cypress Trees at Lake Chicot State Park
Kim / Adobe Stock

Another fabulous stop on the Great River Road is Lake Village and Lake Chicot in Arkansas, which is Lake Chico State Park. Lake Chicot is an abandoned river channel 20 miles along and is Arkansas’ largest natural lake.

Visitors can enjoy the swimming area or walk along the lakeside trail in downtown Lake Village. There are also picnic areas and a boat ramp. Nearby is the Lakeport Plantation, the only antebellum plantation home remaining on the Arkansas portion of the river.

Fully restored in the Greek Revival style, the house has exhibits for the public and is one of Arkansas State University’s heritage sites.

There are few hotel options in Lake Village, but on the other side of the river, about 13-miles away in Greenville, Mississippi, is the charming Skylight. It’s within walking distance of several restaurants and a casino.

See Related: Inspiring Songs About Traveling

Best Cities for Seeing the Mississippi River

These cities have it all, each a prime spot on the Mississippi and vibrant city attractions.

10. New Orleans, Louisiana

Musicians Playing Instrument in French Quarter, New Orleans

This famous city in Louisiana is known for its bars, halls, and restaurants serving spicy everything. The culture of New Orleans is a fusion of French and African.

Part of the fun of New Orleans is its lore of pirates, ghosts, priestesses, fortune-tellers, and more. If you dare, come for Mardi Gras – the famously rowdy Louisiana carnival!

In the historical New Orleans French Quarter, the river is at its deepest of 191 feet deep and the current by this point is quite strong.

Watch the steamboats cruise by or spend an afternoon in Old Algiers and enjoy the sights of the great river, which ends its 2,000-mile journey to the Gulf of Mexico.

Close to the French Quarter and next to the river, the Westin New Orleans is the ultimate in Louisiana hospitality and perfect for couples visiting “the Big Easy.”

See Related: Do You Need a Rental Car in New Orleans

11. St. Louis, Missouri

Gateway Arch and Skyline View in St. Louis, Missouri

One of the most intriguing structures in America is the mile-long Chain of Rocks Bridge with its 30-degree turn in the middle as it spans the river. It’s a landmark on Route 66 and it gets its name from the Chain of Rocks rapids just north of the city.

Since they were dangerous for boats to navigate, the Corps of Engineers built a dam to cover them. But the bridge still stands and brings visitors to St. Louis from all over. The Chain of Rocks Bridge is not the only reason to see St. Louis. Or drive Route 66!

There’s the Alton Visitors Center along the Great River Road with exhibits and information about the rivers in St Louis. You can also visit the Audubon Center at Riverlands & Riverlands Migratory Bird Sanctuary, which is the gateway to nature in St. Louis. There are trails and scenic overlooks here.

There is also the Columbia Bottom Conservation Area containing 800 acres of forest and wetlands which is a habitat for eagles. And, of course, the famous Gateway Arch is an incredible monument and icon in the city. St. Louis is ideal for a family vacation on the Mississippi River.

Stay in the heart so you can take in all the attractions around the river, St. Louis sightseeing, and the Arch. The Drury Plaza St. Louis at the Arch is highly rated and centrally located.

See Related: Things to Do in St. Charles, Missouri

12. La Crosse, Wisconsin

Overview of River and Forest in La Crosse, Wisconsin

This picturesque city sits on the river as it starts its journey south. River fans can visit the Riverside Museum to learn about the area’s history.

Riverboat cruises depart from Riverside Park for a different water experience. There are also numerous trails for walking and hiking in La Crosse, Wisconsin.

Overall, this is a lovely city for a relaxing getaway. The Gundersen Hotel & Suites is centrally located and highly rated.

Fun Things to Do in Mississippi

Planning a vacation in Mississippi? Here are some fun river-related options.

13. Tunica River Park and Museum

Architecture of Tunica River Park and Museum by the Mississippi River
ploughman8 / TripAdvisor

This is great for things to do in Mississippi with kids. You’ll get incredible scenic overlooks of the river and natural history education.

The museum is closed on Sundays and Mondays, but the beautiful park has very nice biking and walking trails and is open all week.

Tunica is a popular destination known for its entertaining things to do in northern Mississippi at its casinos, lounges, and resorts.

If you’re not traveling with kids, treat yourself to some fun in an exciting casino, relax by the pool, or take in a show at the Gold Strike Casino Resort.

14. River Road Queen Welcome Center & Museum of the Delta

The state’s welcome centers have been known as Mississippi tourism attractions, too, because of how they look like antebellum buildings and have exhibits showing river history and culture.

One is the River Road Queen Welcome Center & Museum of the Delta at the Washington County Welcome Center. With a Victorian-era riverboat facade, it was part of the State of Mississippi Exhibit in the 1984 New Orleans World’s Fair.

Now, it’s one of the cool free things to do in Mississippi, serving to welcome visitors to Mississippi state and its portion of the river.

It can get a little busy but it makes an interesting stopping point for a break as you enter the state. If you’re traveling as a couple or with friends and looking for a great hotel in nearby Greenville, you’ll like the convenient location of Tru By Hilton.

15. Grand Gulf Military Park

Chapel in the Forest of Grand Gulf Military Park
Grand Gulf Military Park / Grand Gulf Military Park

One of the best Mississippi points of interest and historic places is the Grand Gulf Military Park, located on the river in the small town of Port Gibson, between Vicksburg and Natchez.

It’s full of Mississippi history, featuring old photographs, models, and artifacts about the area and the days when the Grand Gulf was a bustling place and then a Civil War battleground. A fascinating observation tower shows where and how the Confederates defended the site against Union shelling.

It’s small and peaceful now, and it is one of the many places to visit in Mississippi of interest to Civil War and American history buffs. Near the park, the Canemount Plantation Inn is a gracious bed & breakfast with a refreshing pool, terrace, and daily American breakfast.

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